A. AUTO – AND ALLO-IMMUNITY FOLLOWING ISLET TRANSPLANTATION

Pubblicazioni Scientifiche

• AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

  Insulin resistance, intramyocellular lipid content, and plasma adiponectin in patients with type 1 diabetes

• AMERICAN JOURNAL OF TRANSPLANTATION

  Rapamycin induces a caspase-independent cell death in human monocytes

• AMERICAN JOURNAL OF TRANSPLANTATION

  Culture medium modulates proinflammatory conditions of human pancreatic islets before transplantation

• AMERICAN JOURNAL OF TRANSPLANTATION

  High levels of donor CCL2/MCP-1 predict graft-related complications and poor graft survival after kidney-pancreas transplantation

• AMERICAN JOURNAL OF TRANSPLANTATION

  The clinical impact of islet transplantation

• AMERICAN JOURNAL OF TRANSPLANTATION

  Improving the Procedure for Detection of Intrahepatic Transplanted Islets by Magnetic Resonance Imaging

• AMERICAN JOURNAL OF TRANSPLANTATION

  Disengaging the IL-2 Receptor with Daclizumab Enhances IL-7-Mediated Proliferation of CD4+ and CD8+ T Cells

• BLOOD

  Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets

• BLOOD

  Bone marrow as an alternative site for islet transplantation

• CANCER RESEARCH

  Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4

• CELL TRANSPLANTATION

  Disproportionate Hyperproinsulinemia, β-Cell Restricted Prohormone Convertase 2 Deficiency, and Cell Cycle Inhibitors Expression by Human Islets Transplanted Into Athymic Nude Mice: Insights Into Nonimmune-Mediated Mechanisms of Delayed Islet Graft Failure

• CELL TRANSPLANTATION

  Intrahepatic Islet Transplant in the Mouse: Functional and Morphological Characterization

• CELL TRANSPLANTATION

  MR Imaging Monitoring of Iron-Labeled Pancreatic Islets in a Small Series of Patients: Islet Fate in Successful, Unsuccessful, and Autotransplantation

• CLINICAL AND EXPERIMENTAL IMMUNOLOGY

  Association of interferon-γ and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes

• DIABETES

  Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance

• DIABETES

  Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-Cells

• DIABETES CARE

  Kidney function after islet transplant alone in type 1 diabetes - Impact of immunosuppressive therapy on progression of diabetic nephropathy

• DIABETIC MEDICINE

  Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission

• DIABETOLOGIA

  Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes

• DIABETOLOGIA

  Beta cell chromogranin B is partially segregated in distinct granules and can be released separately from insulin in response to stimulation

• DIABETOLOGIA

  Ghrelin-producing epsilon cells in the developing and adult human pancreas

• DIABETOLOGIA

  Beta cell function during rapamycin monotherapy in long-term type 1 diabetes

• INTERNATIONAL JOURNAL OF CARDIOLOGY

  Left ventricular function and energy homeostasis in patients with type 1 diabetes with and without microvascular complications

• ISLETS

  Rapamycin does not adversely affect intrahepatic islet engraftment in mice and improves early islet engraftment in humans

• JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

  Tissue factor and CCL2/monocyte chemoattractant protein-1 released by human islets affect islet engraftment in type 1 diabetic recipients

• JOURNAL OF CLINICAL INVESTIGATION

  Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells

• JOURNAL OF IMMUNOLOGY

  Tumor-derived MUC1 mucins interact with differentiating monocytes and induce IL-10high IL-12low regulatory dendritic cell

• JOURNAL OF IMMUNOLOGY

  Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes

• JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

  Stem cells and the kidney: A new therapeutic tool?

• REGENERATIVE MEDICINE

  Diabetes mellitus: an opportunity for therapy with stem cells?

• TRANSPLANT INTERNATIONAL

  Rapamycin in islet transplantation: friend or foe?

• TRANSPLANTATION

  Rapamycin impairs antigen uptake of human dendritic cells

• TRANSPLANTATION

  Donor and isolation variables associated with human islet monocyte chemoattractant protein-1 release

• TRANSPLANTATION

  Relevance of hyperglycemia on the timing of functional loss of allogeneic islet transplants: Implication for mouse model