Analisi delle alterazioni neuronali associate a mutazioni nel gene TM4SF2 a rescue mediante terapie genetiche e farmacologiche

Pubblicazioni Scientifiche

• ACS CHEMICAL NEUROSCIENCE

  Biosynthesis of Astrocytic Trehalose Regulates Neuronal Arborization in Hippocampal Neurons

• CELLULAR AND MOLECULAR LIFE SCIENCES

  AMPAR trafficking in synapse maturation and plasticity

• CEREBRAL CORTEX

  Pharmacological Modulation of AMPAR Rescues Intellectual Disability-Like Phenotype in Tm4sf2-/y Mice

• METABOLOMICS

  Biosynthesis of glycerol phosphate is associated with long-term potentiation in hippocampal neurons

• MOLECULAR AND CELLULAR NEUROSCIENCE

  Tetraspanins shape the synapse

• NATURE COMMUNICATIONS

  Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission