GENETIC AND FUNCTIONAL CHARACTERIZATION OF THE MOLECULAR DEFECTS IN THE LONG QT SYNDROME

Pubblicazioni Scientifiche

• ALLERGY

  Evaluation of the cardiac safety of second-generation antihistamines

• BIOCHEMICAL PHARMACOLOGY

  Human ether-a-gogo related gene (HERG) K+ channels as pharmacological targets

• BRITISH JOURNAL OF PHARMACOLOGY

  Inhibition of HERG1 K+ channels by the novel second-generation antihistamine mizolastine

• CIRCULATION

  A recessive variant of the Romano-Ward Long-QT syndrome?

• CLINICAL AND EXPERIMENTAL ALLERGY

  Cardiac ion channels and antihistamines: possible mechanisms of cardiotoxicity

• EUROPEAN JOURNAL OF PHARMACOLOGY

  Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells

• HUMAN MOLECULAR GENETICS

  Cellular dysfunction of LQT5-minK mutants:: abnormalities of IKs, IKr and trafficking in long QT syndrome

• JOURNAL OF NEUROSCIENCE

  Do glia have heart?: Expression and functional role for ether-a-go-go currents in hippocampal astrocytes

• MOLECULAR PHARMACOLOGY

  Modulation of the K+ channels encoded by the human ethera-gogo-related gene-1 (hERG1) by nitric oxide

• MOLECULAR PHARMACOLOGY

  Pharmacological blockade of ERG K+ channels and Ca2+ influx through store-operated channels exerts opposite effects on intracellular Ca2+ oscillations in pituitary GH3 cells

• MOLECULAR PHARMACOLOGY

  Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines

• TRENDS IN PHARMACOLOGICAL SCIENCES

  Cardiotoxic potential and CNS effects of first-generation antihistamines